BDBM50110676 CHEMBL280487::okadaic acid
SMILES C[C@@H](C[C@H](O)[C@H]1O[C@@H]2CC[C@@]3(CC[C@@H](O3)\C=C\[C@@H](C)[C@@H]3CC(C)=C[C@@]4(O[C@H](C[C@@](C)(O)C(O)=O)CC[C@H]4O)O3)O[C@H]2[C@H](O)C1=C)[C@H]1O[C@@]2(CCCCO2)CC[C@H]1C
InChI Key InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50110676
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type R96A by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against serine/threonine protein phosphatase 1(PP1)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type D220V by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type H248N by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type N124D by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type E275R by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild typeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type R221S by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type Y272F by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type D208A by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type C127S by compound was evalutadeMore data for this Ligand-Target Pair